A few users have experienced negative side effects. One felt drowsy, while others have experienced excessive sweating, muscle and chest pain, deep vein thrombosis, and trouble walking. This mainly occurred in older users. In a study on 64 patients with osteoarthritis (OA), taking Celadrin capsules for 68 days improved knee flexibility and decreased aches and pains compared to the placebo group [ 5]. A study involving 172 people with osteoarthritis of the knee compared the use of a arnica gel with a prescribed, nonsteroidal anti-iflammatory gel (the NSAID piroxicam) with 1g of gel applied three times a day for 4 weeks. The results showed a pain reduction of 16.5 in the arnica gel group versus only 8.1 in the NSAID gel group and the researchers concluded that the Arnica gel was at least as effective and as well tolerated as the NSAID gel. A similar trial involving over 200 people with osteoarthritis of the hands showed that arnica gel was just as effective as an NSAID (ibuprofen) gel in reducing pain and improving hand function.

We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. It is a mixture of cetylated fatty acids, which are formed by combining naturally occurring fats with cetyl alcohol.

In This Review

Different creams and gels combine different pain-relieving ingredients for a greater, synergistic effect. The most effective natural ingredients are arnica, cannabidiol CBD oil, glucosamine, chondroitin, celadrin, comfrey root, capsicum, MSM and Green-lipped mussel extracts. The most effective pharmaceutical pain relief gel are those containing diclofenac, which is a stronger version of ibuprofen. Celadrin® supplements have actually been available for several years, however initially such products were obtained from bovine sources which restricted its popularity. Fortunately Celadrin® is now available from a plant-based source, with oils including palm, palm kernel, olive, nutmeg, coconut and unsaturated vegetable oils. Additionally these new supplements are Vegan and Vegetarian friendly.

The sensation of rubbing literally helps to drown out any pain messages coming from that area. In the same way, the physical action of massaging in a cream or gel stimulate touch receptors and other nerve endings which send signals to the brain. This overwhelms messages from pain receptors so their signals are less likely to get through. Medical Disclaimer: This product/supplement review is not intended to provide diagnosis, treatment, or medical advice. Please consult with a physician or other healthcare professional regarding any medical or health-related diagnosis or treatment options. Celadrin mediate anti-inflammatory effects and increased levels of EPA or DHA has shown to decrease the levels of PGE2 and 4 series-LT. In safety terms it has been rigorously tested and has been found to be totally safe and well absorbed. In some cases adjustments to the diet can help to improve the symptoms of joint problems. Many sufferers also use nutritional food supplements as part of their regime and the common ones are glucosamine, chrondroitin, MSM and omega 3 (fish oils). More recently a product called Celadrin® has emerged as a new and exciting natural food supplement to aid joint mobility and flexibility, subdue the inflammatory process and reduce pain.There is no safety data about dosage in young children, pregnant or nursing women, and people with severe liver or kidney disease. These sensitive groups should avoid Celadrin just in case. Drug Interactions The double-blind, multi-centre, placebo-controlled trial examined the impact of a 68-day oral administration of Celadrin on 64 participants who were experiencing joint and mobility problems. MSM (methyl-sulfonyl-methane) is a naturally rich source of sulphur which is a vital constituent of connective tissues and structural proteins. It is essential for the repair of muscles, joints and ligaments and has a powerful antioxidant and anti-inflammatory action. Hi Paul, This is not a condition I’m very familiar with. I’ve done a bit of research for you and found that most people will regain up to 70-90% of their original strength and functional levels within two years. The same reference suggests that ‘Specific pain medications used to treat PTS include opiates and non-steroidal anti-inflammatory drugs (NSAIDs), which are usually used in combination. … After the acute phase, different medications such as gabapentin, carbamazepine, and amitryptiline may be used specifically to treat nerve pain.’ It’s possible that diclofenac gel will help the pain – this is the most effective topical NSAID available without prescription. Your doctor can prescribe other versions. Nerve pain is difficult to treat topically, although capsaicin cream (chilli extract) is prescribed to treat other forms of nerve pain eg related to shingles. Physio will help the nerves to recover – a medical herbalist may be able to suggest herbal creams that might promote nerve regrowth. Hope that helps. Menthol, Levomenthol, Eucalyptus, Camphor and Oil of Wintergreen are often added to topical joint treatments. These essential oils are absorbed into the skin and stimulate skin receptors to produce either a warm sensation or a cooling sensation as they numb the pain. They work by overwhelming nerve endings with these sensations so pain messages do not get passed on. This is known as a counter-irritant effect. Wintergreen is also a rich source of methyl salicylate, a natural anti-inflammatory painkiller related to aspirin. These essential oil creams and gels tend to have names such as Deep Heat or Deep Freeze to describe how they feel during use. Voltarol pain gel