Staudacher HM, Whelan K. Altered gastrointestinal microbiota in irritable bowel syndrome and its modification by diet: probiotics, prebiotics and the low FODMAP diet. Proc Nutr Soc 2016;75:306-18. [ PubMed abstract] Kadooka Y, Sato M, Ogawa A, Miyoshi M, Uenishi H, Ogawa H, et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial. Br J Nutr 2013;110:1696-703. [ PubMed abstract] Zhao M, Shen C, Ma L. Treatment efficacy of probiotics on atopic dermatitis, zooming in on infants: a systematic review and meta-analysis. Int J Dermatol 2018;57:635-41. [ PubMed abstract] Certain unfermented foods, such as milks, juices, smoothies, cereals, nutrition bars, and infant and toddler formulas, have added microorganisms. Whether these foods are truly probiotics depends on the microorganism levels they contain when they are eaten, whether they survive intestinal transit, and whether their specific species and strains have health effects. Dietary supplements

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Microorganisms ( Lactobacillus acidophilus CUL60 & CUL21, Bifidobacterium animalis subsp. lactis CUL34, Bifidobacterium bifidum CUL20), Vegetarian Capsule Shell (Hydroxypropyl Methylcellulose), Microcrystalline Cellulose, Anti-caking Agents (Silicon Dioxide, Magnesium Stearate). No allergens Our digestive system (gut) is central to supporting our health – it contains more than 70% of the body’s immune system and 10 times more bacteria than we have cells in our whole body (the gut microbiome). Bosch M, Fuentes MC, Audivert S, Bonachera MA, Peiro S, Cune J. Lactobacillus plantarum CECT 7527, 7528 and 7529: probiotic candidates to reduce cholesterol levels. J Sci Food Agric 2014;94:803-9. [ PubMed abstract] Overall, the available evidence suggests that the use of probiotics might reduce the risk of developing atopic dermatitis and lead to significant reductions in atopic dermatitis SCORAD scores, but these products might provide only limited relief from the condition. Furthermore, the effects of probiotics vary by the strain used, the timing of administration, and the patient’s age, so it is difficult to make recommendations. Pediatric acute infectious diarrhea Whether different strains of probiotic bacteria have beneficial effects on IBS probably depends on the IBS symptom being evaluated [ 48]. In a meta-analysis of 10 RCTs with a total of 877 adults treated with probiotics or placebo for 4 weeks to 6 months, pain scores improved significantly with administration of probiotics containing Bifidobacterium breve, Bifidobacterium longum, or Lactobacillus acidophilus species compared with placebo treatment [ 49]. In contrast, Streptococcus salivarius ssp. thermophilus, Bifidobacterium animalis, Bifidobacterium infantis, Lactobacillus casei, Lactobacillus plantarum, Lactobacillus bulgaricus, and Saccharomyces boulardii had no significant effect. The abdominal distension scores improved with use of probiotics containing Bifidobacterium breve, Bifidobacterium infantis, Lactobacillus casei, or Lactobacillus plantarum species. Flatulence declined with use of all tested probiotics, but the studies showed no positive effect of probiotics on quality of life.Keeping our children healthy is a primary focus for parents and here at ProVen, we understand how difficult it can be to get our kids to eat a healthy diet each day. Lorenzo-Zuniga V, Llop E, Suarez C, Alvarez B, Abreu L, Espadaler J, et al. I.31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life. World J Gastroenterol 2014;20:8709-16. [ PubMed abstract]

A Healthy Gut for a Healthy Life Concentrated - Probiotics

Wilkins T Sequoia J. Probiotics for gastrointestinal conditions: a summary of the evidence. Am Fam Physician 2017; 96: 170-8. [ PubMed abstract] Microorganisms ( Lactobacillus acidophilus CUL60 & CUL21, Lactobacillus gasseri CUL09, Bifidobacterium animalis subsp. lactis CUL34, Bifidobacterium bifidum CUL20), Microcrystalline Cellulose, Vegetarian Capsule Shell (Hydroxypropyl Methylcellulose), Cranberry Extract ( Vaccinium macrocarpon), Anti-caking Agents (Silicon Dioxide, Magnesium Stearate, Tricalcium Phosphate), Corn Maltodextrin, Magnesium Hydroxide, Vitamin B6 (Pyridoxine Hydrochloride). No allergens Didari T, Solki S, Mozaffari S, Nikfar S, Abdollahi M. A systematic review of the safety of probiotics. Expert Opin Drug Saf 2014;13:227-39. [ PubMed abstract] Production by lactobacilli and bifidobacteria of short-chain fatty acids, which lower hepatic cholesterol synthesis and regulate cholesterol metabolism [ 50-53]

International Scientific Association for Probiotics and Prebiotics. Deciphering a probiotic label . 2017. The product contains Lab4, the most researched group of friendly bacteria in the UK, along with Lactobacillus plantarum, an additional strain of live bacteria to provide a high-strength multi-strain product – with a total of 50 billion live bacteria per capsule. American Gastroenterological Association. Consideration for use of probiotics in gastrointestinal diseases: clinical decision support tool. Gastroenterology 2020; 159: 706. [ PubMed abstract] If using alongside antibiotics, ensure that ProVen Probiotics Acidophilus & Bifidus – 50 Billion is taken a minimum of 2 hours away from antibiotic intake. Directions for use