Absolute Aromas Valerian 5ml Essential Oil - 100% Pure, Natural, Undiluted and Vegan Friendly

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Behboodi Moghadam Z, Rezaei E, Shirood Gholami R, Kheirkhah M, Haghani H. The effect of valerian root extract on the severity of pre menstrual syndrome symptoms. J Tradit Complement Med. 2016 Jan 19;6(3):309-15. View abstract. The drowsiness caused by valerian root grows stronger over time, so the chances are that you’ll feel more sleepy after an hour than you would after 30 minutes. If you only need a slight nudge to get you to sleep, then you probably won’t need to take your valerian root too long before you go to bed. Cerny A, Shmid K. Tolerability and efficacy of valerian/lemon balm in healthy volunteers (a double blind, placebo-controlled, multicentre study). Fitoterapia 1999;70:221-8. Yuan CS, Mehendale S, Xiao Y, et al. The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesth Analg 2004;98:353-8. View abstract. Ortiz, J. G., Nieves-Natal, J., and Chavez, P. Effects of Valeriana officinalis extracts on [3H]flunitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release. Neurochem.Res 1999;24(11):1373-1378. View abstract.

Hubner, R., van, Haselen R., and Klein, P. Effectiveness of the homeopathic preparation Neurexan compared with that of commonly used valerian-based preparations for the treatment of nervousness/restlessness - an observational study. ScientificWorldJournal. 2009;9:733-745. View abstract. As with other herbs, caution should be taken when using valerian root alongside other substances and medications. Lin, S., Zhang, Z. X., Chen, T., Ye, J., Dai, W. X., Shan, L., Su, J., Shen, Y. H., Li, H. L., Liu, R. H., Xu, X. K., Wang, H., and Zhang, W. D. Characterization of chlorinated valepotriates from Valeriana jatamansi. Phytochemistry 2013;85:185-193. View abstract. Gessner, B. and Klasser, M. [Studies on the effect of Harmonicum Much on sleep using polygraphic EEG recordings]. EEG.EMG.Z.Elektroenzephalogr.Elektromyogr.Verwandte.Geb. 1984;15(1):45-51. View abstract. Valerian essential oil can be used for aromatherapy in a diffuser, use as many drops as you see fit. Valerian essential oil’s earthy scent pairs divinely with many other oils. Diffuse your favorite Valerian-infused blend to start the chill.Alcohol can cause sleepiness and drowsiness. Valerian might also cause sleepiness and drowsiness. Taking large amounts of valerian along with alcohol might cause too much sleepiness. Cuellar NG, Ratcliffe SJ. Does valerian improve sleepiness and symptom severity in people with restless legs syndrome? Altern Ther Health Med 2009;15:22-8. View abstract. A systematic review and meta-analysis including 16 evidence-based studies indicates that valerian root is widely used and respected by the general population and physicians for its sedative effects and anti-anxiety capab

While research into how valerian works for sleep is still ongoing, studies indicate that the impact of this substance might have something to do with its interactions with the GABA receptors in the brain.Bonnet MH, et al. Treatment of insomnia in adults. https://www.uptodate.com/contents/search. Accessed Dec. 28, 2017. Houghton PJ. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol 1999;51:505-12. View abstract. Hellum BH, Hu Z, Nilsen OG. The induction of CYP1A2, CYP2D6 and CYP3A4 by six trade herbal products in cultured primary human hepatocytes. Basic Clin Pharmacol Toxicol. 2007 Jan;100:23-30. View abstract.

Valerian Essential Oil is steam distilled from the roots of Valeriana officinalis. This pretty plant produces pretty pinkish white flowers, but it's the roots that are responsible for the extraordinarily relaxing properties that valerian is known for. Sun J. Morning/evening menopausal formula relieves menopausal symptoms: a pilot study. J Altern Complement Med 2003;9:403-9. View abstract.GABA, or gamma aminobutyric acid, contributes to the calmness and relaxation you feel in your body and mind. Common prescription drugs for anxiety typically work by increasing GABA levels in the brain.

In this study, based on the “weighting factor” network pharmacology and transcriptome sequencing, we found that the serotonergic synapse is a possible pathway of action of valerian oil for insomnia. To further test our conjecture, we used the PCPA method to create a rat insomnia model, administered different doses of valerian essential oil during the experiment and observed the behavior of the rats. The results showed that the intervention of rats with insomnia using valerian essential oil could increased the protein expression of 5-HT1AR, ADCY5, PKA, and GABAA in the hippocampus, increase the serum levels of 5-HT and GABA, decreased the DA level, and increased the mRNA transcripts of 5-HT1AR, ADCY5, PKA, and GABAA in the hippocampus of rats. Moreover, the rats treated with valerian essential oil gradually regained circadian rhythms, stable emotions, moist fur, and a significant increase in body mass. Based on the available research, it seems likely that taking around 300mg to 600mg of valerian root before bedtime is a good idea. Valerian tincture Maroo N, Hazra A, Das T. Efficacy and safety of a polyherbal sedative-hypnotic formulation NSF-3 in primary insomnia in comparison to zolpidem: a randomized controlled trial. Indian J Pharmacol 2013;45(1):34-9. View abstract.

For instance, in one study from 2009, women with insomnia took 300mg of valerian extract 30 minutes before going to bed and reported no significant improvements into the quality of their sleep.