FRONTLINE Plus also contains the important addition of (S)-methoprene which acts as an insect growth inhibitor. (S)-methoprene works to prevent the multiplication of fleas by inhibiting the development of the immature stages of growth (eggs, larvae and pupae) for up to 6 weeks of application. NatWest, RBS and Ulster Bank to close at least 172 branches in 2023/24 – here's the full list, plus alternatives Martin Lewis: What the Autumn Statement means for you – including wages, benefits, pensions, ISAs, housing, national insurance and more FRONTLINE PLUS ® contains fipronil and (S)-methoprene. UK: AVM-GSL. FRONTLINE TRI-ACT ® contains fipronil and permethrin. UK: NFA-VPS. FRONTLINE ® SPOT ON contains fipronil. UK: AVM-GSL. Boehringer Ingelheim is a research-driven group of companies dedicated to the discovery, development, manufacture and marketing of innovative health care products. Section Overview

Frontline Tri-Act Spot-On usually dries within 2-4 hours. The active ingredients in Frontline Tri-Act Spot-On, fipronil and permethrin, are both fast-acting and the product dries within 2-4 hours of application. However, it is still important to avoid bathing your pet for at least 48 hours after application.

I was a few days late with the Frontline in October, and ever since then although I have been dosing them all every 4 weeks as usual I have been finding fleas and one of my poor cats has been pulling her fur out near her tail. Still had live fleas jumping around on her - mature fleas - not ones that had just jumped on -ones with egg filled abdomens. I started flea combing...cos it was so bad.

Martin Lewis: What the Autumn Statement means for you – including wages, benefits, pensions, ISAs, national insurance and more NatWest, Royal Bank of Scotland (RBS) and Ulster Bank, which are all part of the NatWest Group, will now shut at least 172 of their bank branches in 2023 and 2024. The Chancellor Jeremy Hunt has today (Wednesday 22 November) announced a range of tax, benefits and savings measures. We round up the key announcements and what they mean for you. I Frontlined them again as soon as the 28 days were up from the last dose and that was about a week ago, so I am giving it a few days more to see if the scabs heal and if not it's vets time.The main difference between Frontline Spot-On and Frontline Plus is that Frontline Plus contains an additional active ingredient, (S)-methoprene, which prevents flea eggs and larvae from developing. This means that Frontline Combo can provide more comprehensive protection against fleas, as it can help to break the flea lifecycle. I suggest you reinvestigate the lifecycle of the flea - they stay on the pet (host) lay eggs which fall off with the flea dirt (flea poo - dried blood) -the eggs hatch and the larvae eat the flea dirt. They go through a couple of instars (moults) and then pupate. They can remain dormant as pupae for years until they are disturbed ...that's how they over winter outside - but as long as it isn't freezing as soon as they are disturbed (CO2/vibrations etc) they emerge as adult fleas - jump on a pet, feed and breed - which takes about 48hrs. They can survive on human blood for months they jump on and off but they can't reproduce. ) Fleas have such a short life cycle that it is believable that some have become resistant. We have issues about antibiotic resistance - bacteria do have a shorter lifecycle but rats (much longer lifecycle) became resistant to warfarin....actually headlice are known to be becoming resistant to some treatments. And if you continue to use these ineffective treatments you are 'selecting for' resistant fleas/bacteria/etc - only the resistant ones survive and thrive (natural selection).