This serum really gives my rough and dull skin a refreshing and clear smooth look. While purchasing this serum, I was not sure if it will really work for my skin . Other (less serious) concernsare if EGF can properly penetrate the skin (as it is a medium-sized, polar molecule, so a special deliverysystem is probably needed), if it can affectcollagen synthesis (or just works on the surface plumping up only the upmost layers of the skin) and if it has beneficial effects at all when used in isolation versus when used in a "conditioned media" that contains lots of growth factors resembling the synergistic balance found in the skin. When it comes to Sh-Oligopeptide-1 in a cosmetic product, it haspretty well-established woundhealing and skin renewal properties. It might even do more than that. According to a 2012 study on a serumcontaining barley bioengineered epidermal growth factor, "clinical evaluations showed statistically significant improvement in the appearance of fine lines and rhytids, skin texture, pore size, and various dyschromatic conditions apparent within the first month of use, and continuing improvement trends for the duration of the study" (which was 3 months). SAP (the vit C derivative, not the enterprise software, obvs) is a promising derivative that has great stability up to pH 7. The challenge with it thoughis skin penetration. Unfortunately, it seems to be limited, or to quote a great article from theJournal of Cosmetic Dermatology "topically applied ascorbyl phosphate salts are, at very best, poorly absorbed in comparison with AA". Regarding conversion to AA, there seems to be no data about it, so we can neither deny nor confirm it. We have better news regarding the three magic abilities of vitamin C: there is in-vivo (tested on real people) data showing that SAP does have photo-protective (aka antioxidant) properties, though less than pure AA. SAP might also aid collagen boosting;in-vitro (made in the lab) data shows that it works, but is less effective than another vitamin C derivative, called MAP (that seems to be as effective as pure AA). As for skin-brightening, there is a trade publication with in-vivo data showing that SAP can fade brown spots.

This all sounds amazing, "give me some EGF Serum", we can hear you say! But as we wrote in the intro, the topic is complex and controversial so here are some of the questions that keep coming up around slathering EGF all over our face.Have you tried this serum? Is vitamin C part of your routine? Would love to hear from you in the comments section below!

You can also use it at night or mix it with cream. See all of Wishtrend’s top tips here. What I like about it Another thing SAP might be able to do is to help with acne. A 2005 study showed in vitro (in test tubes) that 1% SAP has a strong antimicrobial activity on evil acne causing P. acnes and it also showed in vivo (on real people) that 5% SAP can strongly improvethe inflammatory and non-inflammatory lesions of acne vulgaris. In fact, the results were comparable or even slightly better than with 5% benzoyl peroxide. Centella Asiatica also often shows up in products that try to treat cellulite or striae. Of course, it cannot make a miracle but it might have some effect via regulating microcirculation and normalizing the metabolism in the cells of connective tissues. Madecassoside can also help in burn wound healing through increasing antioxidant activity and enhancing collagen synthesis. Asiaticoside was shown to increase antioxidant levels on rats skin when applied at 0.2%. A little goes a long way. After 3 months of daily use, my little bottle is still half full which is awesome.Now as promised, here is a little bit of info about shopping for the right Vitamin C serum, because there are a few things you should know... And call me old-fashioned, but I like it when my products last longer than a month. That’s a lot of serious wastage if you have to buy yourself a new bottle of serum every month when you’re not even halfway done with it. I hope you enjoyed my 2-part series on Vitamin C! Let me know if you have any questions about it or your thoughts on Vitamin C below.

I use Klairs Freshly Juiced Vitamin Drop in my morning routine — after toner, before moisturizer and sunscreen.Bạn nên bảo quản sản phẩm ở nhiệt độ bình thường, nơi thoáng mát. Nếu có thể thì bảo quản chúng trong tủ lạnh thì sử dụng sẽ thích hơn.