Women who are breastfeeding. (It's not known if phenylephrine passes into breast milk, or its effect on a nursing infant. When taken by mouth, decongestants such as phenylephrine can also temporarily decrease the production of breast milk with just one or two doses. Ask your doctor or pharmacist for further advice.) With phenylephrine there is a possibility that an increased risk of arrhythmias may occur in patients receiving cardiac glycosides or tri-cyclic anti-depressants. Phenylephrine interacts with monoamine oxidase inhibitors; it should not therefore, be taken by patients receiving monoamine oxidase inhibitors or within 14 days of stopping such medication. Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required, the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24 hours from ingestion should be discussed with the NPIS or a liver unit. If you are pregnant or breastfeeding, talk to your doctor or pharmacist before taking this medicine If you take Benylin mucus cough & cold all-in-one relief in the hour before or the six hours after taking colestyramine, the paracetamol is likely to be less effective. This is because colestyramine reduces the absorption of paracetamol from the gut.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with the ingredients of Benylin mucus cough & cold all-in-one relief. Just because a side effect is stated here doesn't mean that all people using this medicines will experience that or any side effect. The antidiabetic medicines exenatide, lixisenatide and liraglutide may slow down the absorption of paracetamol into the bloodstream, so it might take longer to work if you're using one of these medicines to treat your diabetes. Ask your pharmacist for more advice.

Why Benylin®

Liver damage is possible in adults who have taken 10g or more of paracetamol. Ingestion of 5g or more of paracetamol may lead to liver damage if the patient has risk factors (see below). Co-administration with medicines containing e.g. propylene glycol or ethanol may lead to accumulation of ethanol and induce adverse effects, in particular in young children with low or immature metabolic capacity. Concomitant use of phenylephrine with other sympathomimetic amines can increase the risk of cardiovascular side effects. For adults, the recommended dose of dextromethorphan is 10 mg to 20 mg taken by mouth every 4 hours, or 30 mg taken by mouth every 6 to 8 hours. The maximum daily dose for adults is 120 mg.

Expectorants such as guaifenesin are used to treat a productive, chesty or mucus cough, where you cough up phlegm. Guaifenesin helps to thin and loosen the mucus in the airways, making it easier to cough up. Paracetamol should be used with care in patients with severe renal or hepatic impairment. The hazard of overdose is greater than those with non–cirrhotic alcoholic liver disease.

Do not take with other cold or decongestant medicines or any other paracetamol-containing products.

The active ingredients per 20ml are: paracetamol 1000mg, phenylephrine hydrochloride 12.18mg, guaifenesin 200mg, cetylpyridinium chloride 3mg Symptoms of paracetamol overdosage in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. Cardiac arrhythmias and pancreatitis have been reported. Medical conditions:Talk to your doctor or pharmacist about using this product if you have serious kidney or liver disease, high blood pressure, heart or thyroid disease, diabetes, asthma, chronic lung disease or shortness of breath, persistent or chronic cough, glaucoma, difficulty urinating due to enlargement of prostate gland, chronic alcoholism, or any other medical condition or are taking medications for depression.Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention. Contains paracetamol. Talk to a doctor at once if you take too much of this medicine, even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage. For children 6 to 11 years of age, the recommended dose is 5 mg to 10 mg taken by mouth every 4 hours. The maximum daily dose for children is 60 mg.

Pregnancy:This medication should not be used during pregnancy unless the benefits outweigh the risks. If you are pregnant, talk to your doctor or pharmacist before taking this medication. There may be different strengths of dextromethorphan products available. Make sure you read the label and ask your doctor or pharmacist how much and how often you should take it. It is important that this medication be taken exactly as recommended by your doctor or pharmacist, or as indicated on the product label. This medicinal product contains 31 mg of sodium per dose. To be taken into consideration by patients on a controlled sodium diet.Seniors:If you are a senior, talk to your doctor or pharmacist before taking this medication. What other drugs could interact with this medication? Undesirable effects are rare with normal doses of phenylephrine, however it can cause the adverse effects typical of sympathomimetics including: hypertension, palpitations (tachycardia), headache, dizziness, vomiting, diarrhoea and insomnia. Urinary retention has also been reported – this is more likely to occur in men with an enlarged prostate (frequency not known).