The first known cultivation of opium poppies was in Mesopotamia, approximately 3400 BCE, by Sumerians, who called the plant hul gil, the "joy plant". [11] [12] Tablets found at Nippur, a Sumerian spiritual center south of Baghdad, described the collection of poppy juice in the morning and its use in production of opium. [1] Cultivation continued in the Middle East by the Assyrians, who also collected poppy juice in the morning after scoring the pods with an iron scoop; they called the juice aratpa-pal, possibly the root of Papaver. [13] Opium production continued under the Babylonians and Egyptians. Armero and Rapaport. The Arts of an Addiction. Qing Dynasty Opium Pipes and Accessories (privately printed, 2005) Protocol for Limiting and Regulating the Cultivation of the Poppy Plant, the Production of, International and Wholesale Trade in, and Use of Opium Before the 1920s, regulation in Britain was controlled by pharmacists. Pharmacists who were found to have prescribed opium for illegitimate uses and anyone found to have sold opium without proper qualifications would be prosecuted. [94] With the passing of the Rolleston Act in Britain in 1926, doctors were allowed to prescribe opiates such as morphine and heroin if they believed their patients demonstrated a medical need. Because addiction was viewed as a medical problem rather than an indulgence, doctors were permitted to allow patients to wean themselves off opiates rather than cutting off any opiate use altogether. [95] The passing of the Rolleston Act put the control of opium use in the hands of medical doctors instead of pharmacists. Later in the 20th century, addiction to opiates, especially heroin in young people, continued to rise and so the sale and prescription of opiates was limited to doctors in treatment centers. If these doctors were found to be prescribing opiates without just cause, then they could lose their license to practice or prescribe drugs. [95] W. R. Martin & H. F. Fraser (September 1, 1961). "A comparative study of subjective and physiological effects of heroin and morphine administered intravenously in postaddicts". Journal of Pharmacology and Experimental Therapeutics. 133 (3): 388–399. PMID 13767429 . Retrieved June 6, 2007.

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Great Britain, India office (1922). The truth about Indian opium. [London] Printed by H.M. Stationery Off. Simon O'Dochartaigh. "HON Mother & Child Glossary, Meconium". hon.ch. Archived from the original on May 1, 2021 . Retrieved April 4, 2016. Stephen Harding; Lee Ann Olivier & Olivera Jokic. "Victorians' Secret: Victorian Substance Abuse". Archived from the original on May 31, 2007 . Retrieved May 2, 2007. W. Travis Hanes III; Frank Sanello (February 1, 2004). The Opium Wars: The Addiction of One Empire and the Corruption of Another. Sourcebooks. pp.88–. ISBN 978-1-4022-5205-1. David William Bebbington (1993). William Ewart Gladstone: Faith and Politics in Victorian Britain. Wm. B. Eerdmans Publishing. pp.108–. ISBN 978-0-8028-0152-4.This section needs to be updated. Please help update this article to reflect recent events or newly available information. ( October 2022) Ms Louise Foxcroft (June 28, 2013). The Making of Addiction: The 'Use and Abuse' of Opium in Nineteenth-Century Britain. Ashgate Publishing, Ltd. pp.66–. ISBN 978-1-4094-7984-0. In June 2007, the council launched a "Poppy for Medicines" project that provides a technical blueprint for the implementation of an integrated control system within Afghan village-based poppy for medicine projects: the idea promotes the economic diversification by redirecting proceeds from the legal cultivation of poppy and production of poppy-based medicines. [140] There has been criticism of the Senlis report findings by Macfarlan Smith, who argue that though they produce morphine in Europe, they were never asked to contribute to the report. [141] Cultivation in the UK [ edit ] Operational Medicine 2001 Field Medical Service School Student Handbook: Molle medical bag/surgical instrument set". December 7, 1999 . Retrieved June 27, 2007. Peter Dale Scott, Asia-Pacific Journal Japan Focus, 1 Nov. 2010, Volume 8 | Issue 44 | Number 2, "Operation Paper: The United States and Drugs in Thailand and Burma" 米国とタイ・ビルマの麻薬

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Marc Andre Matten, ed. (December 9, 2011). Places of Memory in Modern China: History, Politics, and Identity. BRILL. p.271. ISBN 978-90-04-21901-4. Smoking of opium came on the heels of tobacco smoking and may have been encouraged by a brief ban on the smoking of tobacco by the Ming emperor. The prohibition ended in 1644 with the coming of the Qing dynasty, which encouraged smokers to mix in increasing amounts of opium. [1] In 1705, Wang Shizhen wrote, "nowadays, from nobility and gentlemen down to slaves and women, all are addicted to tobacco." Tobacco in that time was frequently mixed with other herbs (this continues with clove cigarettes to the modern day), and opium was one component in the mixture. Tobacco mixed with opium was called madak (or madat) and became popular throughout China and its seafaring trade partners (such as Taiwan, Java, and the Philippines) in the 17th century. [47] In 1712, Engelbert Kaempfer described addiction to madak: "No commodity throughout the Indies is retailed with greater profit by the Batavians than opium, which [its] users cannot do without, nor can they come by it except it be brought by the ships of the Batavians from Bengal and Coromandel." [20] Suzanne Carr (1995). "MS thesis". Archived from the original on November 8, 2009 . Retrieved May 16, 2007. (citing Andrew Sherratt)Bradley, James (2009). The Imperial Cruise: a secret history of empire and war. Little, Brown and Company. pp. 274–275. ISBN 978-0-316-00895-2. Forbes, Andrew; Henley, David (2011). Traders of the Golden Triangle. Chiang Mai: Cognoscenti Books. ASIN B006GMID5K In 1856 a similar incident led to a second ‘Opium War’ with the British navy shelling Canton and opening up other ports. The opium trade increased again so that up to 15 million Chinese became regular opium smokers. The Chinese authorities made opium use legal and began to grow their own poppies. Within a few decades Chinese opium production outstripped the Indian grown supplies and British sales and influence declined. In time China became a main supply for opium use in Europe.

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This opium latex is about 12% morphine, which is the opiate that is used to produce heroin and other synthetic opioids. The latex also contains the opiates, codeine and thebaine. Benjamin Pui-Nin Mo & E. Leong Way (October 1, 1966). "An Assessment Of Inhalation As A Mode Of Administration Of Heroin By Addicts". Journal of Pharmacology and Experimental Therapeutics. 154 (1): 142–151. PMID 5924312 . Retrieved June 6, 2007. John K. Fairbanks, "The Creation of the Treaty System' in John K. Fairbanks, ed. The Cambridge History of China, vol. 10 Part 1 (Cambridge University Press, 1992) p. 213. cited in John Newsinger (October 1997). "Britain's opium wars – fact and myth about the opium trade in the East". Monthly Review. Archived from the original on February 13, 2006. Lomax, Elizabeth (1973). "The Uses and Abuses Of Opiates In Nineteenth-Century England". Bulletin of the History of Medicine. 47 (2): 167–176. ISSN 0007-5140. JSTOR 44447528. PMID 4584236 . Retrieved May 31, 2022.

a b c d e Alfred W. McCoy. "Opium History, 1858 to 1940". Archived from the original on April 4, 2007 . Retrieved May 4, 2007. El Zahrawi – Father Of Surgery". Archived from the original on September 27, 2007 . Retrieved May 4, 2007. a b c d Philip Robson (1999). Forbidden Drugs. Oxford University Press. p. 161. ISBN 978-0-19-262955-5. Opium timeline". The Golden Triangle. Archived from the original on April 20, 2009 . Retrieved September 13, 2009. a b Rewriting history, A response to the 2008 World Drug Report, Transnational Institute, June 2008