Evans, M., Rumberger, J., Azumano, I., Napolitano, J. J., Citrolo, D., & Kamiya, T. (2014, February 27). Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: A triple-blinded placebo and diet-controlled investigation. Vascular Health and Risk Management, 10, 89-100 Vitamin B5, also called pantothenic acid, is one of the most important vitamins for human life. It’s necessary for making blood cells, and it helps you convert the food you eat into energy.

Because of the fact that it works both as a humectant and an emollient, panthenol is excellent for repairing the damaged skin barrier. Several things can damage the skin’s barrier function. We mean the oils that your skin barrier needs to stay intact and functional (3). Because of its moisturizing abilities, panthenol keeps the skin soft and reduces roughness and flakiness. 3. It soothes. It can also be applied to the skin to relieve itchiness and promote healing from skin conditions, such as: NIVEA’s Daily Essentials Extra Gentle Eye Make-Up Remover is formulated to gently remove your unwanted make-up from the day, while hydrating the delicate skin around the eye area.Baby products. Because panthenol is safe for skin, you can even find some baby products with it. These include baby shampoo, lotion, soap, and sunscreen. Be sure to monitor your baby’s skin to determine if certain products give them skin rashes or not. Health Effects of Panthenol Panthenol is a crystalline, white powder derived from pantothenic acid. Panthenol converts to vitamin B5 when applied to the skin which is why it is also known as Pro vitamin b5. Budde, J., Tronnier, H., Rahlfs, V. W., and Frei-Kleiner, S. [Systemic therapy of diffuse effluvium and hair structure damage]. Hautarzt 1993;44(6):380-384. View abstract. Raczynska, K., Iwaszkiewicz-Bilikiewicz, B., and Stozkowska, W. [Gel with provitamin B5 applied during tests with the Goldmann triple-mirror]. Klin.Oczna 2003;105(3-4):179-181. View abstract. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. View abstract.

Patassini S, Begley P, Xu J, et al. Cerebral vitamin B5 (D-pantothenic acid) deficiency as a potential cause of metabolic perturbation and neurodegeneration in Huntington's disease. Metabolites. 2019;9(6):113. View abstract. Panthenol is a compound derived from pantothenic acid, an essential nutrient the body requires for various functions (like converting food into energy). When applied to the skin, it transforms into vitamin B5 and works as a humectant to attract and retain moisture. Just like hyaluronic acid. However, compared to its counterpart, panthenol is also an emollient, which means it works to soften the skin surface, reduce redness, and restore the skin’s barrier function. [1] Egger, S. F., Huber-Spitzy, V., Alzner, E., Scholda, C., and Vecsei, V. P. Corneal wound healing after superficial foreign body injury: vitamin A and dexpanthenol versus a calf blood extract. A randomized double-blind study. Ophthalmologica 1999;213(4):246-249. View abstract. Gehring, W. and Gloor, M. Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study. Arzneimittelforschung. 2000;50(7):659-663. View abstract. Panthenol works well on your skin because vitamin B5 is extracted with ethanol or benzyl alcohol to dissolve into your skin. This type of topical treatment includes other vitamins and amino acids that are good for your skin.Panthenol is an odourless, slightly bitter, highly viscous, transparent, and colourless liquid at room temperature, [5] but salts of pantothenic acid (for example sodium pantothenate) are powders that are typically white. It is easily soluble in water and alcohol, moderately soluble in diethyl ether, soluble in chloroform (1:100), [5] in propylene glycol, and slightly soluble in glycerin. Vitamin B5 is often added to hair and skin products, as well as makeup. Dexpanthenol, a chemical made from B5, is used in creams and lotions designed to moisturize the skin. Synergetic ingredients: Works well with most ingredients but especially well with humectants like hyaluronic acid and occlusive ingredients that help trap the moisture in the skin. What Is Acetyl Glucosamine? Acetyl glucosamine is a skin-replenishing ingredient that helps to reduc...

Panthenol is considered to be safe for its indicated uses. Given that panthenol is generally well tolerated for most skin types and rarely causes irritation or sensitivity it is safe for use in most formulations.Costa, S. D., Muller, A., Grischke, E. M., Fuchs, A., and Bastert, G. [Postoperative management after cesarean section--infusion therapy and role of intestinal stimulation with parasympathomimetic drugs and dexpanthenon]. Zentralbl.Gynakol. 1994;116(7):375-384. View abstract. Pantothenic acid is vitamin B5. It is widely found in both plants and animals including meat, vegetables, cereal grains, legumes, eggs, and milk.