You can leave it in your mouth for up to 4 hours. What happens if I swallow some of the contents of the pouch? Benko, C. R., Farias, A. C., Farias, L. G., Pereira, E. F., Louzada, F. M., and Cordeiro, M. L. Potential link between caffeine consumption and pediatric depression: A case-control study. BMC.Pediatr 2011;11:73. View abstract.

One review study showed that 300 mg of caffeine per day in healthy pregnant women is safe, with limited data suggesting that 1.1 mg of caffeine per pound (2.5 mg per kg) of body weight in children and adolescents may be safe ( 2). Institute of Medicine (US) Committee on Military Nutrition Research. Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations. Washington (DC): National Academies Press (US); 2001. 2, Pharmacology of Caffeine. Available from: https://www.ncbi.nlm.nih.gov/books/NBK223808/ Supplements. Caffeine supplements contain about 200 mg per tablet, or the amount in 2 cups of brewed coffee. In addition, caffeine consumed later in the day may interfere with sleep because its effects can take several hours to wear off. Caffeine is a stimulant, which means it increases activity in your brain and nervous system. It also increases the circulation of chemicals such as cortisol and adrenaline in the body.Avoid large amounts of caffeine-containing foods and beverages, such as coffee, tea, cocoa, cola drinks, energy drinks and chocolate if you are taking higher doses of caffeine tablets. This also includes any herbal, dietary, or prescription medications that contain caffeine. Parkinson disease: Taking caffeine with creatine might make Parkinson disease worsen faster. If you have Parkinson disease and take creatine, use caffeine with caution. On the other hand, some studies suggest that caffeinated beverages may worsen gastroesophageal reflux disease (GERD) in some people. This seems to be especially true of coffee ( 23, 24, 25).

However, at higher doses, these effects may become more pronounced, leading to anxiety and nervousness. Moreover, the discreet nature of caffeine pouches makes them a practical solution for those moments when you need a caffeine boost but aren’t in a position to drink coffee or an energy drink. They’re perfect for meetings, long drives, or while working, where you might want to avoid the physical act of drinking.Most research looking at the compound’s effects on urinary frequency has focused on older people and those with overactive bladders or incontinence ( 43, 44, 45). Alstott, R. L., Miller, A. J., and Forney, R. B. Report of a human fatality due to caffeine. J.Forensic Sci. 1973;18(2):135-137. View abstract.