There are reports on resistance of Ancylostoma spp to pyrantel in dogs and horses, but so far it does not seem to be widespread, and the simultaneous administration of a benzimidazole ( febantel) with a different mechanism of action than pyrantel should ensure efficacy against potentially pyrantel-resistant worms. Small tablets (Anthelmin Plus Flavour) for small and medium dogs* with 150 mg febantel, 50 mg pyrantel base (as 144 mg pyrantel embonate) and 50 mg praziquantel: one small tablet for every 10 kg bw particular Taenia spp. and Dipylidium caninum .Praziquantel acts against adult and immature forms of

Meaning that they have lost patent protection and may be acquired from manufacturers of generic active ingredients other than the holder of the original patent .Anthelmin Plus XL 1 tablet per 35 kg bodyweight. Tablets may be halved to allow accuracy of dosing. Roundworms ( Toxocara canis, Toxascaris leonina), hookworms ( Ancylostoma caninum , Uncinaria stenocephala) The tablet(s) can be given directly to the dog or disguised in food. No restriction of access to food is required either before or after administration of the product. To ensure administration of a correct dose, body weight should be determined as accurately as possible. Puppies may be wormed with this product from 2 weeks of age and every 2 weeks until 12 weeks of age. Thereafter they should be treated at 3 monthly intervals until 6 months of age.

Special precautions to be taken by the person administering the veterinary medicinal product to animals ANTHELMIN PLUS from KRKA (A Slowenian company) is a generic all-round wormer for dogs with febantel, pyrantel, and praziquantel, effective against roundworms and tapeworms. It is a generic version of DRONTAL from BAYER.Anthelmin Plus Flavour and Anthelmin Plus XL - Consult a veterinary surgeon before treating pregnant animals for roundworms. Never use on cats tablets approved only for use on dogs, and vice-versa. Never use on small dogs tablets approved for large dogs. Learn more about tablets and their safety. For the control of Toxocara, nursing bitches should be dosed 2 weeks after giving birth and every 2 weeks until weaning. For adult dogs, a single dose should be used. The advice of a veterinarian should be sought regarding the need for and frequency of repeat treatment. In the event of a heavy roundworm infestation, a repeat dose should be given after 14 days.

In the interests of good hygiene, persons administering the tablet directly to a dog or by adding it to the dog's food, should wash their hands afterwards. particular, the activity spectrum covers Toxocara canis , Toxascaris leonina , Uncinaria stenocephala and Ancylostoma UK and other countries: 15 mg/kg bodyweight febantel, 5 mg/kg pyrantel base (as 14.4 mg pyrantel embonate) and 5 mg/kg praziquantel.Do not use the product in the first two thirds of pregnancy. The product may be used during lactation. Anthelmin Plus Flavour – For treatment of dogs administer 1 tablet per 10kg bodyweight (15 mg/kg bodyweight febantel, 14.4 mg/kg pyrantel and 5 mg/kg praziquantel). This is equivalent to 1 tablet per 10 kg bodyweight. Tablets may be halved/quartered to allow accuracy of dosing. LD50 (acute oral) in rats: n.a. for the tablets. 1760 mg/kg for febantel; >5000 mg/kg for pyrantel; 2840 mg/kg for praziquantel