Observational studies, like the above, allow the assessment of benefit in real-life settings, but due to the open label un-blinded design without placebo they are more exposed to bias, and the results should therefore be considered as preliminary.

Please be assured that our couriers will work as hard as they can to deliver parcels as normal, and will get your parcel to you as soon as they are able. A positive difference between treatment groups was also seen for the subjects' assessments of global efficacy of the investigational product A robust safety profile for ColdZyme was demonstrated throughout the study. Finally, the trypsin enzymes (responsibly sourced from cod as a sustainable biproduct of the fishing industry) deactivates the virus particles, inhibiting them from infecting cells, multiplying and then spreading. ColdZyme Strawberry Anti Cold/Anti Flu Mouth Spray 20 ml Viruseptin Lozenges against Cold and Flu 20 pc.You can change your choices at any time by visiting Cookie preferences, as described in the Cookie notice.

A Randomized, Double-Blind, Placebo-Controlled Pilot Clinical Study on ColdZyme® Mouth Spray against Rhinovirus-Induced Common Cold.The 9-item WURSS-21 QoL domain composite score, as well as eight out of nine individual QoL items, were found to be the most sensitive instrument for demonstrating that treatment with ColdZyme compared to “no treatment” significantly improved the common colds sufferers’ quality of life.

In the previously referred study [18] athletes who had less than 2 sick days during the preceding months did seem to be less prone to catch a cold during the study period. I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.Pregnancy or nursing, history of or current abuse of drugs, alcohol or medication, participation in the present study of a person living in the same household as the subject, inability to comply with study requirements according to investigator’s judgement or participation in another clinical study in the 30 days prior to enrolment and during the study, were also exclusion criteria. Innovative Scientific Concept of Topical Virus Glycoprotein Inhibitors Incorporated in Hyperosmotic Glycerol Revolutionizes Future Prospects in the Treatment of Viral and Bacterial Throat Infections. The ColdZyme group showed broadly similar scores to the control group in the remaining secondary endpoints comprising the single items and symptoms of the WURSS-21 and Jackson scales, day with maximum score, use of and exposure during the first 4 days to concomitant treatment, duration of the first intense phase, symptom intensity, sore throat scale and number of days sick at home due to common cold. Exclusion criteria included known allergy to the components of the investigational product, a health condition which could interfere with the results of the study or the safety of the subject, influenza vaccination within three months prior to enrolment, and regular use of products that may influence the study outcome, except for the defined optional care.

Glycerol, water, a natural enzyme - cod trypsin, ethanol (<1%) (only in the menthol taste), calcium chloride, trometamol and menthol. The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. They mention that it really works, is natural, and is useful for this particular year when everyone you meet has a cold. With Coldzyme, you're not just treating symptoms – you're fortifying your immune system for a life less interrupted by the discomfort of seasonal illnesses. The investigators’ assessed the efficacy of the investigational product similarly, with ratings “very good” or “good” for 64.Both groups were allowed to use optional care (as”rescue” treatment) comprising paracetamol (acetaminophen), maximum 2 g/day, ibuprofen, maximum 400 mg/day or saline nose drops or spray, if needed for symptom relief. Despite the increased risk in athletes, the number of reported colds in this evaluation is in line with the prevalence for a normal population, which is 2 - 4 incidents per subject and year, mostly during the winter [17] .