Meanwhile, continued studies in the U.S. indicate CBD is effective in treating chronic, non-cancer pain. In one 2020 study, researchers administered CBD topically to a group of patients with symptomatic peripheral neuropathy (a result of brain nerve and spinal cord nerve damage) while another group with the same condition received a placebo. Results showed a significant reduction in intense, sharp pains and cold, itchy sensations in those who used the topical CBD compared to those who used the placebo. No participants reported adverse side effects. Lowe H, Toyang N, Steele B, Bryant J, Ngwa W. The Endocannabinoid System: A Potential Target for the Treatment of Various Diseases. International Journal of Molecular Sciences. 2021;22(17):9472. doi:10.3390/ijms22179472 However, to protect public health, they can take action against CBD companies that make unfounded health claims.

Other ingredients: If the product is, say, a CBD-infused tea, then the rest of the ingredients should be specified. If you want to avoid THC in a CBD product, even in low amounts, look for broad-spectrum or isolate products. Can full-spectrum CBD cause anxiety?Chesney E, et al. (2020). Adverse effects of cannabidiol: A systematic review and meta-analysis of randomized clinical trials. In that case, CBD would restore these deficiencies as CBD is binds those receptors in the brain. The article suggests that Cannabis is a possible solution for Fibromyalgia, as well as migraines. 10. May Help Relieve Cancer Pains & Cancer-Related Symptoms Cather JC, Cather JC. Cannabidiol primer for healthcare professionals. Proc (Bayl Univ Med Cent). 2020;33(3):376-379. Published 2020 Jul 6. doi:10.1080/08998280.2020.1775437

Using human and animal models, multiple studies found that cannabidiol deactivates important HIV-1 cells, and through CB2 agonists, decreased HIV replication. The same study document noted that THC also has benefits against HIV-1 infection. 29. CBD is an effective treatment for heroin addiction: Darkovska-Serafimovska M, et al. (2018). Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases. As we mentioned, CBD’s potential interactions with vitamins, minerals, and supplements, including melatonin, are still unknown. This means it’s safer to avoid products that blend these ingredients since we don’t have research on their safety. In a 2023 review of 34 studies on CBD use for insomnia management, all the studies reported improvement in insomnia symptoms for at least some portion of participants. Osteoarthritis (OA) is a joint disease that has many facets and effects, such as intermittent inflammation, joint degeneration, and peripheral neuropathy.Oils: CBD oils usually contain olive oil, hempseed oil, medium-chain triglyceride (MCT) oil, or another type of oil. The label should specify which type of oil it contains.

Spindle TR, Cone EJ, Kuntz D, et al. Urinary Pharmacokinetic Profile of Cannabinoids Following Administration of Vaporized and Oral Cannabidiol and Vaporized CBD-Dominant Cannabis. Journal of Analytical Toxicology. 2019;44(2):109-125. doi:10.1093/jat/bkz080 Balachandran P, Elsohly M, Hill KP. Cannabidiol Interactions with Medications, Illicit Substances, and Alcohol: a Comprehensive Review. Journal of General Internal Medicine. Published online January 29, 2021. doi:10.1007/s11606-020-06504-8

What Is CBD Oil?

This aid in fear also may help PTSD as well. When traumatic memories are remembered, they are stored as “important” by the brain. By this statement, CBD could disrupt this process, and eventually lead to less severe negative memories being processed. Babayeva M, Assefa H, Basu P, Chumki S, Loewy Z. Marijuana Compounds: A Nonconventional Approach to Parkinson's Disease Therapy. Parkinsons Dis. 2016;2016:1279042. doi:10.1155/2016/1279042 A study ( Epub 2015) on the specific effects of CBD on depression found results that “CBD exerts fast and maintained antidepressant-like effects as evidenced by the reversal of the OBX-induced hyperactivity and anhedonia.” Malfait AM, Gallily R, Sumariwalla PF, et al. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proc Natl Acad Sci U S A. 2000;97(17):9561-9566.