Historically, Lugol's iodine solution has been widely available and used for a number of health problems with some precautions. [28] Lugol's is sometimes prescribed in a variety of alternative medical treatments. [29] [30] Only since the end of the Cold War has the compound become subject to national regulation in the English-speaking world. [ citation needed] Society and culture [ edit ] Regulation [ edit ] antiseptic components it is a great asset to any first aid kit. It cleans and treat cuts, grazes, burns. Iodine is used for skin disinfection before A urine iodine test is most often used in research studies looking into iodine deficiency and is accepted as a good marker of very recent dietary iodine intake 20 although there are some controversies over this test. 28

Less commonly, it is used to replenish iodine deficiency. However, pure potassium iodide, which contains a relatively mild iodide ion without the more toxic elemental iodine, is strongly preferred for this purpose. Includes:Interestingly, there is often an increase in body odour for the first two weeks (which probably represents excretion of toxins) and some patients have cloudy urine for several months. Believe it or not, a teaspoon of iodine will provide us with all the iodine we need for our entire life. Preoperative administration of Lugol's solution decreases intraoperative blood loss during thyroidectomy in patients with Graves' disease. [12] However, it appears ineffective in patients who are already euthyroid on anti-thyroid drugs and levothyroxine. [13] World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl: 10665/345533. WHO/MHP/HPS/EML/2021.02. If you’re eating iodine-rich food as well as these food sources, the risk of developing a deficiency should be minimal. Summary

If the body has sufficient iodine, most of the ingested iodine will be excreted in the urine. The more deficient in iodine the body is, the less iodine will be excreted in the urine. Whole body iodine sufficiency is reached when 90% or more of the ingested amount is excreted in the urine. https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/339439/SACN_Iodine_and_Health_2014.pdf Synthesis of oxytocin using iodine for oxidative cyclization and silica gel adsorption chromatography for purification a b Sneader W (2005). Drug Discovery: A History. John Wiley & Sons. p.67. ISBN 9780471899792. Archived from the original on 26 August 2017.

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It can be difficult to know where to get iodine but there are many foods with naturally-occurring levels of iodine. These include seaweed or sea kelp, fish, meat, cheese and many more. Changes in Dietary Iodine Explains Increasing Incidence of Breast Cancer with Distand Involvement in Young Women Potassium iodide renders the elementary iodine soluble in water through the formation of the triiodide ( I − Please see here for many supporting studies on dosage and efficacy - Optimox - Resources for Iodine Research Related Articles Lugol's iodine was first made in 1829 by the French physician Jean Lugol. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] [10] Lugol's iodine is available as a generic medication and over the counter. [1] Lugol's solution is available in different strengths of iodine. Large volumes of concentrations more than 2.2% may be subject to regulation. [11] Uses [ edit ] Medical uses [ edit ]

radiological procedure used to visualize abnormalities of the urinary system, including the kidneys, ureters, and bladder. These amounts do not reflect the optimum amount of micronutrient for optimum health. The two amounts (i.e. the RDA and the optimum amount) for individual micronutrients may be very different and this is well illustrated by iodine. It is now assumed that iodine is only necessary for the production of thyroid hormones, but actually breast tissue requires just as much and deficiency results in fibrocystic disease of the breast and in breast cancer. It is notable that countries with the highest iodine intake have the lowest risk of breast cancer. Indeed, a tendency to cysts generally, including polycystic ovaries, may well be an iodine problem. See the table below for how the body uses iodine:

What is iodine?

American physicians then used between 12.5mg and 37.5mg daily to treat both hyper and hypothyroidism, with some patients requiring 90mg daily. This resulted in a 90% success rate for treatment. It became recognised that there was a pandemic of iodine deficiency. As a result of this, iodised table salt was introduced generally and the benefits of iodine supplementation were forgotten. However, iodine and iodides compete with the other halides (such as fluoride, chloride, bromide) for absorption. Iodine deficiency has been made much more common in recent years because many people are subjected to high levels of fluoride because of their water supply or because of dental treatments; bromide was routinely used in bread making and also as a fire retardant. Thus the high levels of fluorides and bromides in our diet and the environment mean that we are all at great risk of iodine deficiency. Furthermore, the recommended daily amount of iodine is 150 μg - that is to say a thousand fold less than the sort of doses that were used in the 19th century. Not only does Iodine play an important role in the brain, it also contributes to the normal production of thyroid hormones and normal thyroid function. Iodine, thyroxine (T4), triiodothyronine (T3), 3,3′,5′-triiodothyronine (rT3), 3,3′-diiodothyronine (T2) in normal human thyroids. Effect of excessive iodine exposure Patients at high risk of oesophageal squamous cell carcinoma are usually followed using a combination of Lugol’s chromoendoscopy and narrow-band imaging. [14] With Lugol’s iodine, low-grade dysplasia appears as an unstained or weakly stained area; high-grade dysplasia is consistently unstained. [15]

Hawkins PR, Holliday J, Kathuria A, Bowling L (2005). "Change in cyanobacterial biovolume due to preservation by Lugol's Iodine". Harmful Algae. 4 (6): 1033–1043. doi: 10.1016/j.hal.2005.03.001. Iodine can be used to treat conditions associated with excessive production of scar tissue such as keloid, Peyronie's disease and Dupytron's contracture. If your doctor has confirmed that you are deficient, there are several options but you do need to be careful because too much supplementation can cause problems.You could try increasing your iodine levels by eating foods that contain iodine before you try supplementation. health guard. An essential trace element. Safe in this dosage but DO NOT OVERDOSE ! That would be toxic! and 10% ( wt/v) potassium iodide (KI) mixed in distilled water and has a total iodine content of 126.4mg/mL. The (nominal) 5% solution thus has a total iodine content of 6.32mg per drop of 0.05 mL; the (nominal) 2% solution has 2.53mg total iodine content per drop.

The richest food sources of iodine are fish, milk and dairy products. When it comes to fish, white fish contains more iodine than oily fish. Iodine contributes to the normal production of thyroid hormones and normal thyroid function, is important for visual function and eye moisture and may contribute to preserve healthy hair, nails and skin as well as the normal functioning of the nervous system, cognitive function and metabolism.