Individuals with limited effective sun exposure due to protective clothing or consistent use of sun screens Vitamin D has been linked to the prevention of many different diseases, including multiple sclerosis, arthritis and even cancer. Children with higher vitamin D levels are less likely to suffer from asthma and allergies than those who are vitamin D deficient. Mental agility might be maintained by adequate levels of the vitamin, especially in the elderly.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes any medicines which you have bought without a prescription. Ocular supplements are onthe Items which should not be routinely prescribed in primary care(in Lutein and antioxidants section) due to insufficient evidence to support effectiveness at reducing progression of AMD.Never throw away medicine via household or water waste. Take any unwanted or expired medicine to your local pharmacy and ask them to dispose of them safely on your behalf.

Colecalciferol 1 000 IU is the equivalent of 25 micrograms vitamin D 3, which is involved in bone formation.Vitamin D is one of the only vitamins that your body can produce by itself. What is the catalyst that gets your D production going? Good old fashioned sunshine! It’s the ultraviolet-B radiation (UVB) that enables vitamin D production to occur in the skin. Acute or chronic overdose of Colecalciferol can cause hypercalcaemia, an increase in the serum and urinary concentrations of calcium. The symptoms of hypercalcaemia are not very specific and consist of nausea, vomiting, diarrhoea often in the early stages and later constipation, anorexia, fatigue, headache, muscle and joint pain, muscle weakness, polydipsia, polyuria formation of renal calculi, nephrocalcinosis, kidney failure, calcification of soft tissues, changes in ECG measurements, arrhythmias and pancreatitis. In rare and isolated cases there are reports that hypercalcaemia is fatal.

A normalisation of hypercalcaemia due to vitamin D intoxication lasts several weeks. The recommendation for the treatment of hypercalcaemia is the avoidance of any further administration of vitamin D, including supplements, dietary intakes and the avoidance of sunlight. A low calcium or calcium-free diet can also be considered. Medicines suitable to be prescribed in primary care / general practice after specialist* recommendation or initiation.

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May be used orally for reversal of excessive anticoagulation. See SFH warfarin guidelines or NUH guideline on the management of excessive coumarin anticogulation in adults