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If you know you have this genetic mutation or suspect it, then taking supplements that are in their active form can help support optimum methylation. The 7 Nutrients Needed for Methlylation Include: In fact, one study found that treating seven B12-deficient people with oral methylcobalamin normalized vitamin B12 levels in their blood within just 2 months ( 13). Methylation requires a specific B vitamin to be present in the body – 5-MTHF (also known as methylfolate). Optimum support - Methylated forms of B vitamins have been shown to be better absorbed and used by the body B9 (folate). Folate is needed for cell growth, amino acid metabolism, the formation of red and white blood cells, and proper cell division. It can be found in foods like leafy greens, liver, and beans or in supplements in the form of folic acid ( 7).
Additionally, the MTHFR genetic mutation can affect how your body metabolizes folate, which can lead to a folate deficiency and other health concerns ( 21). Since B vitamins are found in many foods, you are most likely not at risk of developing a deficiency as long as you follow a well-rounded diet. Another major difference between methylcobalamin and cyanocobalamin is the way they’re absorbed and retained within your body. Lamberts ® Methyl B Complex is a superior and comprehensive B Complex supplement. Rather than folic acid, it provides a type of folate called methylfolate (or 5-MTHF), since folate is the natural form found in food such as leafy green vegetables and is already active and ready for the body to use. We have specifically chosen to use Quatrefolic ®, the most advance form of folate supplementation available with optimum stability and bio-availability to ensure optimal methylation. It’s involved in the metabolism of fats and amino acids, as well as the formation of myelin, which creates a protective sheath around your nerve cells ( 9).B1 (thiamine). Thiamine plays an essential role in metabolism by helping convert nutrients into energy. The richest food sources include pork, sunflower seeds, and wheat germ ( 1). Since B vitamins are water-soluble, it’s unlikely that you will consume too much of these nutrients through food or by taking a B-complex supplement as directed. B12 (cobalamin). Perhaps the most well-known of all the B vitamins, B12 is vital for neurological function, DNA production, and red blood cell development. B12 is found naturally in animal sources like meats, eggs, seafood, and dairy ( 8).
A daily B-complex vitamin can help ensure that people who choose to follow diets that eliminate animal products are getting enough of these important nutrients. People taking certain medicationsAdditionally, several animal studies have found that each form could have neuroprotective effects and may be beneficial in treating conditions that affect your nervous system ( 16, 17). SUMMARY When cyanocobalamin enters your body, it’s converted into either methylcobalamin or adenosylcobalamin, which are the two active forms of vitamin B12 in humans ( 1). As you age, your ability to absorb vitamin B12 decreases and your appetite declines, making it difficult for some people to get enough B12 through diet alone.
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